Author/Authors :
Tetik, Şermin Marmara Üniversitesi - Eczacılık Fakültesi - Biyokimya Anabilim Dalı, Turkey , Ak, Koray Marmara Üniversitesi - Tıp Fakültesi - Kalp ve Damar Cerrahisi Anabilim Dalı, Turkey
Title Of Article :
Platelet function tests on cardiovascular dieases: from pathophysiology to clinical approach
Abstract :
Platelets have significant functions in thrombosis, hemostasis and inflammation. Antithrombotic therapy has been proven to be important in reduction of mortality and morbidity related to cardiovascular diseases. Recently, many studies have been focused on antithrombotic drug resistance. With this regard, platelet function tests have been gaining more popularity to test the effectiveness of antithrombotic drugs. However, correlation between in vivo and ex vivo platelet functions has not been documented clearly. In this review, we aimed to discuss platelet function tests used in the diagnosis of cardiovascular diseases, advantages and disadvantages of these tests, altered responses to antithrombotic therapy and resistance to antithrombotic therapy.
NaturalLanguageKeyword :
Platelet function tests , antiplatelet treatment , resistance to antiplatelet treatment
JournalTitle :
Cumhuriyet Medical Journal
