Author/Authors :
TERİM KAPAKİN, Kübra A. Atatürk University - Faculty of Veterinary Medicine - Department of Pathology, Turkey , HAZIROĞLU, Rıfkı Ankara Üniversitesi - Faculty of Veterinary Medicine - Department of Pathology, Turkey , GÜRSAN, Nesrin Atatürk University - Faculty of Medicine - Department of Pathology, Turkey , YÜCEL, Gözde Ankara Üniversitesi - Faculty of Veterinary Medicine - Department of Pathology, Turkey
Title Of Article :
Mesothelioma in a dog
Abstract :
In this study a mesothelioma case observed in a four–year-old female Rottweiler dog was defined. Macroscopically, on the serosal surfaces of the stomach and intestines, numerous masses showing diffuse distribution, greyish yellow in colour and hard consistency were observed. Microscopically, tumour cells were predominantly spindle-shaped with moderate amounts of eosinophilic cytoplasm and ovoid nuclei. These cells was not stained with epithelial membrane antigen (EMA) staining, the epithelial marker, while stained with the epithelial marker pancytokeratin and mesenchymal marker vimentin in the avidin-biotin-peroxidase (ABC-P) method. As a result, tumor case seen in a dog s stomach and intestinal serosal surface was defined as a mesothelioma according to the histopathological and immunohistochemical findings.
NaturalLanguageKeyword :
Dog , immunohistochemistry , mesothelioma
JournalTitle :
Veterinary Journal of Ankara University