Author/Authors :
Özkorucuklu, Sabriye Perçin Süleyman Demirel Üniversitesi - Fen Edebiyat Fakültesi - Kimya Bölümü, Turkey , Şahin, Yücel Anadolu Üniversitesi - Fen Fakültesi - Kimya Bölümü, Turkey , Alsancak, Güleren Süleyman Demirel Üniversitesi - Fen Edebiyat Fakültesi - Kimya Bölümü, Turkey
Title Of Article :
Use of Polypyrrole as a Potentiometric Detector in High Performance Liquid Chromatography
Abstract :
In this study, the chromatographic behaviors of four sulfonamides (sulfanilamide, sulfadiazine, sulfamerazine, sulfamonomethoxine) were investigated by a HPLC using polypyrrole as a potentiometric detector. The effect of acetonitrile-water ratio and pH were determined for %15, 30, 40 and 50 (v/v) acetonitrile/water binary mixture between pH 1.5 and 7.0 prepared Britton-Robinson buffers,. The polypyrrole potentiometric detector was prepared by electropolymerization on the surface of glassy carbon. Detection limits of these compounds were calculated as: 1.92.10^-6 M for sulfanilamide; 2.12.10^-6 M for sulfadiazine; 1.83.10^-6 M for sulfamerazine; 1.25.10^-6 M for sulfamonomethoxine.
NaturalLanguageKeyword :
Sulfonamide , Polypyrrole , Potentiometric detector , HPLC
JournalTitle :
Süleyman Demirel University Faculty of Arts and Science Journal of Science
