• DocumentCode
    1029441
  • Title

    Detector identification through light separation for miniature imaging probe

  • Author

    Janecek, Martin ; Hoffman, Edward J. ; Iwanczyk, Jan S. ; Patt, Bradley E. ; MacDonald, Lawrence ; Ghazarossian, Vartan ; Strauss, H.William

  • Author_Institution
    David Geffen Sch. of Med., Univ. of California, Los Angeles, CA, USA
  • Volume
    51
  • Issue
    3
  • fYear
    2004
  • fDate
    6/1/2004 12:00:00 AM
  • Firstpage
    636
  • Lastpage
    640
  • Abstract
    Coronary artery disease (CAD) is the leading cause of death in most developed countries. A large portion of CAD is caused by rupture of unstable plaque, which is not detected by current diagnostic methods. By labeling the unstable plaque with beta emitting radioisotopes, it is possible to detect the plaques with a very narrow in situ detector system that is placed with a coronary angiography guidewire. Our current detection system uses fiber optics, with a single detector at the tip of each fiber, connected to a position-sensitive photomultiplier tube (PSPMT). The small diameter of the coronary artery limits our current system to six optical fibers. To increase the number of pixels, we are studying a multidetector concept for each fiber. By having multiple scintillating fibers coupled in series, with each scintillating fiber emitting a unique wavelength spectrum, the number of pixels can be doubled or tripled. The light is separated before reaching the PSPMT with a single diffraction grating. The PSPMT separates the detectors in one direction by fiber, and in the other direction by the spectral splitting of the different wavelengths of the scintillators.
  • Keywords
    angiocardiography; biomedical equipment; diffraction gratings; optical fibres; photomultipliers; solid scintillation detectors; beta emitting radioisotopes; beta-ray detectors; biomedical applications; biomedical nuclear imaging; coronary angiography guidewire; coronary artery disease; detector identification; fiber optics; in situ detector system; light separation; miniature imaging probe; multidetector; nuclear cardiography; nuclear radiation; optical fibers; position-sensitive photomultiplier tube; scintillating detectors; single diffraction grating; Angiography; Arteries; Coronary arteriosclerosis; Labeling; Optical fibers; Optical imaging; Photomultipliers; Position sensitive particle detectors; Probes; Radioactive materials; Beta-ray detectors; biomedical applications of nuclear radiation; biomedical nuclear imaging; gratingsnuclear cardiography; optical fibers; scintillating detectors;
  • fLanguage
    English
  • Journal_Title
    Nuclear Science, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9499
  • Type

    jour

  • DOI
    10.1109/TNS.2004.829604
  • Filename
    1310576