DocumentCode
1029441
Title
Detector identification through light separation for miniature imaging probe
Author
Janecek, Martin ; Hoffman, Edward J. ; Iwanczyk, Jan S. ; Patt, Bradley E. ; MacDonald, Lawrence ; Ghazarossian, Vartan ; Strauss, H.William
Author_Institution
David Geffen Sch. of Med., Univ. of California, Los Angeles, CA, USA
Volume
51
Issue
3
fYear
2004
fDate
6/1/2004 12:00:00 AM
Firstpage
636
Lastpage
640
Abstract
Coronary artery disease (CAD) is the leading cause of death in most developed countries. A large portion of CAD is caused by rupture of unstable plaque, which is not detected by current diagnostic methods. By labeling the unstable plaque with beta emitting radioisotopes, it is possible to detect the plaques with a very narrow in situ detector system that is placed with a coronary angiography guidewire. Our current detection system uses fiber optics, with a single detector at the tip of each fiber, connected to a position-sensitive photomultiplier tube (PSPMT). The small diameter of the coronary artery limits our current system to six optical fibers. To increase the number of pixels, we are studying a multidetector concept for each fiber. By having multiple scintillating fibers coupled in series, with each scintillating fiber emitting a unique wavelength spectrum, the number of pixels can be doubled or tripled. The light is separated before reaching the PSPMT with a single diffraction grating. The PSPMT separates the detectors in one direction by fiber, and in the other direction by the spectral splitting of the different wavelengths of the scintillators.
Keywords
angiocardiography; biomedical equipment; diffraction gratings; optical fibres; photomultipliers; solid scintillation detectors; beta emitting radioisotopes; beta-ray detectors; biomedical applications; biomedical nuclear imaging; coronary angiography guidewire; coronary artery disease; detector identification; fiber optics; in situ detector system; light separation; miniature imaging probe; multidetector; nuclear cardiography; nuclear radiation; optical fibers; position-sensitive photomultiplier tube; scintillating detectors; single diffraction grating; Angiography; Arteries; Coronary arteriosclerosis; Labeling; Optical fibers; Optical imaging; Photomultipliers; Position sensitive particle detectors; Probes; Radioactive materials; Beta-ray detectors; biomedical applications of nuclear radiation; biomedical nuclear imaging; gratingsnuclear cardiography; optical fibers; scintillating detectors;
fLanguage
English
Journal_Title
Nuclear Science, IEEE Transactions on
Publisher
ieee
ISSN
0018-9499
Type
jour
DOI
10.1109/TNS.2004.829604
Filename
1310576
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