Separation of Magnetic Nanoparticles by Cyclical Electrical Field Flow Fractionation

Author

Tasci, T.O. ; Manangon, E. ; Fernandez, D.P. ; Johnson, W.P. ; Gale, B.K.

Author_Institution

Dept. of Bioeng., Univ. of Utah, Salt Lake City, UT, USA

Volume

49

Issue

1

fYear

2013

fDate

Jan. 2013

Firstpage

331

Lastpage

335

Abstract

In this study, the potential of Cyclical Electrical Field Flow Fractionation (CyEFFF) for the separation of magnetic nanoparticles is investigated. We demonstrated for the first time that by the application of appropriate voltage waveforms, one can separate gold nanoparticles with sizes less than 50 nm. By using suitable voltage waveforms, the detrimental effect of the particle diffusion is suppressed and particles in the range of 10 nms can be fractionated. In addition, it is shown that CyEFFF is capable of separating lipid and polystyrene sulfonate coated magnetite nanoparticles with the same hydrodynamic radius of 50 nm.

Keywords

biomagnetism; biomedical materials; magnetic particles; nanoparticles; particle separators; Ag; CyEFFF technique; cyclical electrical field flow fractionation; gold nanoparticle; hydrodynamic radius; magnetic nanoparticle separation; particle diffusion; voltage waveform; Field-flow fractionation; Lipidomics; Magnetic analysis; Magnetic separation; Nanoparticles; USA Councils; Magnetic nanoparticles; magnetite; separation;

fLanguage

English

Journal_Title

Magnetics, IEEE Transactions on

Publisher

ieee

ISSN

0018-9464

Type

jour

DOI

10.1109/TMAG.2012.2223753

Filename

6392426