Electrokinetic microchip-based sample loading for surface plasmon resonance detection

Author

Xing Chen ; Lulu Zhang ; Haoyuan Cai ; Hui Li ; Jianhai Sun ; Dafu Cui

Author_Institution

State Key Lab. of Transducer Technol., Inst. of Electron., Beijing, China

Volume

8

Issue

1

fYear

2013

fDate

Jan-13

Firstpage

47

Lastpage

51

Abstract

In this reported work, a microfluidic-based fluid electrokinetic force has been used for surface plasmon resonance or surface plasmon resonance image (SPRI) detection. In this device, a modified rectangular microarray of Au instead of previous reported square or circular gold segments was designed and microfabricated with gold segment geometries and characterised by surface morphology studies. A voltage drop of maximal 400 V/cm was applied without gold erosion to drive fluorescein isothiocyanate isomer I in a high-conductivity medium on the bare gold surface layer, enabling SPRI detection.

Keywords

electric potential; electrical conductivity; electrokinetic effects; gold; microfabrication; microfluidics; microsensors; surface morphology; surface plasmon resonance; Au; Au rectangular microarray; SPRI; bare gold surface layer; electrokinetic microchip-based sample; fluorescein isothiocyanate isomer; gold erosion; gold segment geometries; gold segments; high-conductivity medium; microfabrication; microfluidic-based fluid electrokinetic force; surface morphology; surface plasmon resonance detection; surface plasmon resonance image detection; voltage drop;

fLanguage

English

Journal_Title

Micro & Nano Letters, IET

Publisher

iet

ISSN

1750-0443

Type

jour

DOI

10.1049/mnl.2012.0697

Filename

6485120