• DocumentCode
    1136722
  • Title

    Degree of differential prioritization

  • Author

    Ooi, Chia Huey ; Chetty, Madhu ; Teng, Shyh Wei

  • Author_Institution
    Duke-NUS Grad. Med. Sch., Singapore, Singapore
  • Volume
    28
  • Issue
    4
  • fYear
    2009
  • Firstpage
    45
  • Lastpage
    51
  • Abstract
    Because of the high dimensionality of the microarray data sets, feature selection (FS) has become an important challenge in molecular classification. Using the degree of differential prioritization (DDP) between relevance and antiredundancy, our proposed DDP-based FS technique is capable of achieving better accuracies than those previously reported, using a smaller predictor set. However, previously, we have neither devised nor used any method for determining the value of the DDP to be used for the data set of interest before the FS process. In this article, we propose a system for predicting the optimal value of the DDP, which costs less computationally than conventional tuning while maintaining the independence of the FS technique from the type of underlying classifier used.
  • Keywords
    biology computing; classification; degree of differential prioritization; differential prioritization; feature selection; microarray data sets; molecular classification; Computational efficiency; Cost function; Filters; Proposals; Support vector machine classification; Support vector machines; Testing; Algorithms; Data Interpretation, Statistical; Databases, Genetic; Genomics; Models, Genetic; Models, Statistical; Normal Distribution; Oligonucleotide Array Sequence Analysis;
  • fLanguage
    English
  • Journal_Title
    Engineering in Medicine and Biology Magazine, IEEE
  • Publisher
    ieee
  • ISSN
    0739-5175
  • Type

    jour

  • DOI
    10.1109/MEMB.2009.932917
  • Filename
    5165224