DocumentCode :
1161712
Title :
Pinpoint injection of microtools for minimally invasive micromanipulation of microbe by laser trap
Author :
Arai, Fumihito ; Maruyama, Hisataka ; Sakami, Toshihiro ; Ichikawa, Akihiko ; Fukuda, Toshio
Author_Institution :
Precursory Res. for Embryonic Sci. & Technol. Project, Japan Sci. & Technol. Corp., Kawaguchi City, Japan
Volume :
8
Issue :
1
fYear :
2003
fDate :
3/1/2003 12:00:00 AM
Firstpage :
3
Lastpage :
9
Abstract :
This paper reports transportation of the target microbe by the laser trapped microtools with minimum laser irradiation to the target. The size of a microtool (MT) is around micrometer. The MTs are manipulated by the focused laser under the microscope to manipulate the target microbe. Here we propose a pinpoint injection method of MTs at the desired location in the microchamber, which is filled with liquid. At first, we classified the injection method of the MTs in four categories. Here we employed a new method to install the MTs inside the microchamber. We developed a MT holding chip to install the MTs. The MTs were injected in the microchamber, and were manipulated successfully by the laser scanning micromanipulator to transport the target microbe for separation. The proposed method is useful for the pinpoint injection of MTs and separation by the indirect micromanipulation.
Keywords :
biocontrol; micromanipulators; bioengineering; biology; flow cytometer; focused laser; injection method; laser trapped microtools; microbes; microchamber; micromanipulation; microtool; Biomedical optical imaging; Charge carrier processes; Dielectrophoresis; Microchannel; Micromanipulators; Microscopy; Minimally invasive surgery; Power lasers; Systems engineering and theory; Transportation;
fLanguage :
English
Journal_Title :
Mechatronics, IEEE/ASME Transactions on
Publisher :
ieee
ISSN :
1083-4435
Type :
jour
DOI :
10.1109/TMECH.2003.809129
Filename :
1187350
Link To Document :
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