Title :
Batch fabricated thin-film electrodes for stimulation of the central auditory system
Author :
Anderson, David J. ; Najafi, Khalil ; Tanghe, Steven J. ; Evans, David A. ; Levy, Kenneth L. ; Hetke, Jamille F. ; Xue, Xiaolin ; Zappia, John J. ; Wise, Kensall D.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., Michigan Univ., Ann Arbor, MI, USA
fDate :
7/1/1989 12:00:00 AM
Abstract :
Silicon micromachining and thin-film technology were used to fabricate iridium stimulating arrays which can be used to excite discrete volumes of the central nervous system. Silicon multichannel probes with thicknesses ranging from 1 to 40 mu m and arbitrary two-dimensional shape can be fabricated using a high-yield, circuit-compatible process. Iridium stimulating sites are shown to have similar characteristics to iridium wire electrodes. Accelerated pulse testing with over eight million 100 mu A biphasic current pulses on 8000 mu m 2 sites demonstrated the long-term stability of iridium and activated iridium sites. In vivo tests were performed in the central auditory pathways to demonstrate neural activation using the devices. These tests show a selective activation both as a function of site separation and site size.
Keywords :
biological techniques and instruments; hearing; microelectrodes; neurophysiology; thin film devices; 100 muA; Ir stimulating arrays; Si micromachining; accelerated pulse testing; arbitrary 2D shapes; batch-fabricated thin-film electrodes; central auditory system stimulation; central nervous system; multichannel probes; neural activation; Auditory system; Central nervous system; Circuit testing; Electrodes; Micromachining; Probes; Semiconductor thin films; Silicon; Thin film circuits; Transistors; Animals; Auditory Pathways; Electric Stimulation; Equipment Design; Guinea Pigs; Iridium; Materials Testing; Microelectrodes; Silicon;
Journal_Title :
Biomedical Engineering, IEEE Transactions on