A compensation method of light source dynamic tc improve stability of optical fiber-based biosensor

This paper presents a compensation method of light source dynamic to improve a measurement stability of sample´s light transmittance using our fiber optic-based sensor. In principle, dynamic input and transmitted lights are measured for insertion loss calculation of an empty tube. The loss is compensated in the actual light transmittance calculation of a solution sample. Comparison experiments were conducted with double concentration of red syrup solutions. The coefficient of variation (CoV) was used as the stability metric. Results from 2 trials of our double concentration solution samples showed that the COV ranges around 0.987-1.411%. The results from our dynamic compensation approach strongly demonstrated superior measurement stability to the uncompensated approach in which its CoV ranges around 9.075-9.808%.