Title :
The activating function for magnetic stimulation derived from a three-dimensional volume conductor model
Author :
Basser, Peter J. ; Wijesinghe, Ranjith S. ; Roth, Bradley J.
Author_Institution :
Biomed. Eng. & Instrum., Nat. Inst. of Health, Bethesda, MD, USA
Abstract :
A three-dimensional volume conductor model of magnetic stimulation is proposed that relates transmembrane potential of an axon to the induced electric field in a uniform volume conductor. This model validates assumptions used previously to derive a one-dimensional cable model of magnetic stimulation (B.J. Roth and P.J. Basser, ibid., vol.37, p.588-97, 1990) of unmyelinated axons. The three-dimensional volume conductor model reduces to this one-dimensional cable equation forced by the activating function, - delta E A z/ delta z.
Keywords :
bioelectric potentials; biomagnetism; biomembrane transport; neurophysiology; physiological models; activating function; axon; induced electric field; magnetic stimulation; one-dimensional cable equation; three-dimensional volume conductor model; transmembrane potential; Biomembranes; Coils; Conductivity; Conductors; Equations; Extracellular; Magnetic flux; Magnetic stimulation; Nerve fibers; Power cables; Axons; Electromagnetic Fields; Magnetics; Membrane Potentials; Models, Neurological;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
