A novel acoustofluidic device for antigen antibody interaction detection using electrochemical impedance measurement

The advantages of an acoustofluidic biochip includes low cost, deeper penetration depth, non-toxicity, temperature resistant and the ability to stream without presence of micro bubbles. A new acoustofluidic device developed for use as a biosensor is presented. A light-driven transducer was developed to manipulate protein biomarkers by integrating an acoustic radiation force and a gravitational force. We also present results when an acoustofluidic device is incorporated to create a label-free impedance biosensor which can form an assay for protein biomarkers for disease detection. This kind of acoustic field can be used to increase the binding efficiency between antigen and antibodies and save on costs by requiring less sample concentration and amount.