• DocumentCode
    1209751
  • Title

    Sensitivity Analysis and Improved Identification of a Systemic Arterial Model

  • Author

    Paulsen, Robert A., Jr. ; Clark, John W., Jr. ; Murphy, Paul H. ; Burdine, John A.

  • Author_Institution
    Sandia National Laboratories
  • Issue
    3
  • fYear
    1982
  • fDate
    3/1/1982 12:00:00 AM
  • Firstpage
    164
  • Lastpage
    178
  • Abstract
    An identification scheme for the determination of several parameters associated with a third-order lumped-parameter model of the systemic arterial system has been developed previously [1]. In the present study a parameter sensitivity analysis of this model is conducted in conjunction with the identification scheme. This analysis indicates that the state variables of this system are indeed sensitive to changes in the model parameters and initial conditions, but not unduly so. It also indicates the relative sensitivities of individual model parameters and provides valuable insight into the behavior of the arterial model. This insight has resulted in a significant simplification and modification of our identification scheme [1] that makes it more likely to be employed in practice.
  • Keywords
    Arteries; Blood pressure; Brachytherapy; Heart; Hospitals; Parameter estimation; Pediatrics; Pressure measurement; Radiology; Sensitivity analysis; Arteries; Blood Flow Velocity; Blood Pressure; Cardiovascular Physiology; Computers; Humans; Mathematics; Models, Biological;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/TBME.1982.324883
  • Filename
    4121381