DocumentCode
1209751
Title
Sensitivity Analysis and Improved Identification of a Systemic Arterial Model
Author
Paulsen, Robert A., Jr. ; Clark, John W., Jr. ; Murphy, Paul H. ; Burdine, John A.
Author_Institution
Sandia National Laboratories
Issue
3
fYear
1982
fDate
3/1/1982 12:00:00 AM
Firstpage
164
Lastpage
178
Abstract
An identification scheme for the determination of several parameters associated with a third-order lumped-parameter model of the systemic arterial system has been developed previously [1]. In the present study a parameter sensitivity analysis of this model is conducted in conjunction with the identification scheme. This analysis indicates that the state variables of this system are indeed sensitive to changes in the model parameters and initial conditions, but not unduly so. It also indicates the relative sensitivities of individual model parameters and provides valuable insight into the behavior of the arterial model. This insight has resulted in a significant simplification and modification of our identification scheme [1] that makes it more likely to be employed in practice.
Keywords
Arteries; Blood pressure; Brachytherapy; Heart; Hospitals; Parameter estimation; Pediatrics; Pressure measurement; Radiology; Sensitivity analysis; Arteries; Blood Flow Velocity; Blood Pressure; Cardiovascular Physiology; Computers; Humans; Mathematics; Models, Biological;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.1982.324883
Filename
4121381
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