DocumentCode
1222909
Title
A Distributed Model of Iron Kinetics for Clinical Assessment of Normal-Abnormal Erythropoietic Activity
Author
Franzone, Piero Colli ; Stefanelli, Mario ; Viganotti, Carlo
Author_Institution
National Research Council, Laboratorio di Analisi Numerica del Consiglio Nazionale della Richerche, Pavia, Italy, and the School of Engineering, University of Pavia
Issue
10
fYear
1979
Firstpage
586
Lastpage
596
Abstract
The use of mathematical models of iron metabolism has been recognized as an essential tool for analyzing ferrokinetic data. Multicompartment models, however, did not make it possible to describe marrow iron kinetics, taking into account that marrow erythroid cells uptake iron from the plasma according to their maturity.
Keywords
Biochemistry; Biomedical engineering; Blood; Bone diseases; Cells (biology); Councils; Iron; Kinetic theory; Mathematical model; Parameter estimation; Anemia; Bone Marrow; Erythrocytes; Erythropoiesis; Heme; Humans; Iron; Kinetics; Models, Biological;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/TBME.1979.326447
Filename
4122947
Link To Document