• DocumentCode
    1245313
  • Title

    An electronic device for triggering a stimulator during membrane responsiveness determinations in cardiac tissues

  • Author

    Pruett, J.K. ; Francis, W.W.

  • Author_Institution
    Dept. of Anesthesiology, Med. Coll. of Georgia, Augusta, GA, USA
  • Volume
    35
  • Issue
    5
  • fYear
    1988
  • fDate
    5/1/1988 12:00:00 AM
  • Firstpage
    400
  • Lastpage
    402
  • Abstract
    A device is described that monitors the repolarization phase of a cardiac action potential and compares the membrane potential to a voltage selected by the investigator. When the voltages are the same, the device triggers a stimulator that injects the stimulus at the desired membrane potential. The device can stimulate tissue at any membrane potential during the repolarization phase of the action potential between 0 and -100 mV without regard to action potential duration. When it is precisely calibrated, its accuracy is within +or-1.0 mV.
  • Keywords
    bioelectric potentials; biological techniques and instruments; biomembranes; cardiology; 0 to -100 mV; biological instrumentation; cardiac action potential repolarisation phase; cardiac tissues; electronic device; membrane potential; membrane responsiveness determination; stimulator triggering; Biomembranes; Delay effects; Drugs; Operational amplifiers; Optical fiber devices; Pulse amplifiers; Switches; Temperature; Time measurement; Voltage; Action Potentials; Animals; Dogs; Electric Stimulation; Equipment Design; Heart;
  • fLanguage
    English
  • Journal_Title
    Biomedical Engineering, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9294
  • Type

    jour

  • DOI
    10.1109/10.1401
  • Filename
    1401