Title :
Measuring primate RNFL thickness with OCT
Author :
Fox, Joshua ; Marsack, Jason ; Kim, Jeehyun ; Thomsen, Sharon ; Rylander, H. Grady, III ; Milner, Thomas E.
Author_Institution :
Dept. of Biomed. Eng., Texas Univ., Austin, TX, USA
Abstract :
We report results of a study using optical coherence tomography (OCT) to create area maps of the retinal nerve fiber layer (RNFL) thickness. Low-resolution B scans (two-dimensional images) of the in vivo rhesus monkey retina have been recorded in the optic disk, peripapillary area, and macula. Three-dimensional (3-D) renderings of these areas have been created from OCT images and compared to corresponding data from histology. Results of our study indicate: (1) OCT may be utilized to measure the retinal nerve fiber layer thickness in vivo and (2) 3-D surface maps accurately depict the anatomy of the RNFL
Keywords :
biological tissues; biology computing; biomedical measurement; eye; image reconstruction; medical image processing; neurophysiology; optical tomography; rendering (computer graphics); thickness measurement; zoology; 3-D surface maps; OCT interferometer; Wollaston prism; area maps; glaucoma diagnostics; image reconstruction; in vivo rhesus monkey retina; low-resolution B scans; macula; optic disk; optical coherence tomography; peripapillary area; retinal histology; retinal nerve fiber layer thickness; smoothed binary image; three-dimensional renderings; two-dimensional images; Biomedical measurements; Head; In vivo; Nerve fibers; Optical interferometry; Optical losses; Optical recording; Retina; Thickness measurement; Tomography;
Journal_Title :
Selected Topics in Quantum Electronics, IEEE Journal of
DOI :
10.1109/2944.983291
