Title :
Spatio-temporal tracking of myocardial deformations with a 4-D B-spline model from tagged MRI
Author :
Huang, Jiantao ; Abendschein, Dana ; Davila-Roman, Victor G. ; Amini, Amir A.
Author_Institution :
Cardiovascular Image Anal. Lab., Washington Univ., St. Louis, MO, USA
Abstract :
Accurate delineation of the volumetric motion of the left ventricle (LV) of the heart from tagged magnetic resonance imaging (MRI) is an important area of research. The authors have built a system that takes extracted tag line features from short axis (SA) and long axis (LA) image sequences as input and fits a four-dimensional (4-D) time-varying B-spline model to the data by simultaneously fitting the model knot solids to MRI frames via matching three sequences of solid knot planes to the LV tag planes for 4-D tracking. Important advantages of the model are that reconstruction of tag surfaces, three-dimensional (3-D) material point localization, as well as displacement reconstruction are all achieved in a single step. The generated 3-D displacement fields are validated with a cardiac motion simulator, and 3-D motion fields capturing in vivo deformations in a porcine model with posterolateral myocardial infarction are illustrated.
Keywords :
biomechanics; biomedical MRI; cardiology; image motion analysis; image reconstruction; image sequences; medical image processing; muscle; physiological models; splines (mathematics); 3-D motion fields; 4-D B-spline model; LV tag planes; long axis image sequences; magnetic resonance imaging; medical diagnostic imaging; myocardial deformations; porcine model; posterolateral myocardial infarction; short axis image sequences; solid knot planes; spatio-temporal tracking; tagged MRI; Data mining; Deformable models; Feature extraction; Heart; Image reconstruction; Image sequences; Magnetic resonance imaging; Myocardium; Solid modeling; Spline; Animals; Heart Ventricles; Least-Squares Analysis; Magnetic Resonance Imaging; Models, Cardiovascular; Motion; Myocardium; Swine; Time Factors;
Journal_Title :
Medical Imaging, IEEE Transactions on