DocumentCode
1294423
Title
Potential distribution for a spheroidal cell having a conductive membrane in an electric field
Author
Jerry, Rocco A. ; Popel, Aleksander S. ; Brownell, William E.
Author_Institution
Dept. of Biomed. Eng., Johns Hopkins Univ. Sch. of Med., Baltimore, MD, USA
Volume
43
Issue
9
fYear
1996
Firstpage
970
Lastpage
972
Abstract
When a cell is situated in a uniform electric field, the field is modified due to the relatively low conductance of the cell membrane compared to that of the surrounding fluids. In certain cases, such as in the estimation of internal and external electrokinetic forces, one requires a means of estimating the magnitude of the electric field inside and outside the cell. Most treatments consider the case when the membrane has zero conductivity, or the case of only a spherical cell. The authors solve Laplace´s equation for the electric potential distribution inside and outside a cell having a prolate spheroidal shape and having a membrane with a finite, nonzero conductivity.
Keywords
Laplace equations; bioelectric potentials; biomembranes; cellular biophysics; voltage distribution; Laplace´s equation; conductive membrane; external electrokinetic forces; internal electrokinetic forces; prolate spheroidal shape; spheroidal cell potential distribution; uniform electric field; zero conductivity membrane; Auditory system; Biomedical engineering; Biomembranes; Cells (biology); Conductivity; Electric potential; Laplace equations; Neck; Shape; Surgery; Cell Membrane; Cell Physiology; Electric Conductivity; Electromagnetic Fields; Ion Channels; Models, Biological; Surface Properties;
fLanguage
English
Journal_Title
Biomedical Engineering, IEEE Transactions on
Publisher
ieee
ISSN
0018-9294
Type
jour
DOI
10.1109/10.532132
Filename
532132
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