Structure Factor Model for understanding the ultrasonic scattering from concentrated cell pellet biophantoms

Quantitative Ultrasound techniques for determining the tissue microstructure rely on theoretical scattering models to fit the BackScatter Coefficient (BSC) from biological tissues to an estimated BSC using an appropriate model. The models adapted to densely packed cells in tumors are the Structure Factor model (SFM) and the Particle Model (PM, i.e. the low-frequency limit of the SFM), which are generally used in blood characterization. The aim of this work was to use the SFM and the PM to go further in the understanding of the measured BSCs from simple tumor models (i.e. cell pellet biophantoms).