Title :
In vitro simultaneous measurement of refractive index and thickness of biological tissue by the low coherence interferometry
Author :
Ohmi, Masato ; Ohnishi, Yasuhito ; Yoden, Koji ; Haruna, Masamitsu
Author_Institution :
Fac. of Med., Osaka Univ., Japan
Abstract :
The authors proposed and demonstrated in vitro simultaneous measurement of refractive index and thickness of biological tissue. The technique is based on the low coherence interferometry combined with precise translation stages. Refractive indices were determined with the accuracy of less than 1% for tissue samples of a few hundred micron thickness, including chicken tissue, human tooth and nail. Simultaneous measurement of refractive index and thickness of multilayer tissue are also demonstrated.
Keywords :
bio-optics; biological techniques; biological tissues; light coherence; light interferometry; refractive index measurement; thickness measurement; biological research technique; chicken tissue; human nail; human tooth; low coherence interferometry; multilayer tissue; precise translation stages; Biological tissues; Biomedical measurements; Biomedical optical imaging; Humans; In vitro; Optical interferometry; Optical refraction; Optical variables control; Refractive index; Thickness measurement; Animals; Biomedical Engineering; Chickens; Humans; Interferometry; Nails; Optics; Refractometry; Scattering, Radiation; Tooth;
Journal_Title :
Biomedical Engineering, IEEE Transactions on
