Title :
Assessment of 3-D PET quantitation: influence of out of the field of view radioactive sources and of attenuating media
Author :
Ferreira, N.C. ; Trébossen, R. ; Bendriem, B.
Author_Institution :
Servico de Bionsica, Coimbra Univ., Portugal
fDate :
6/1/1998 12:00:00 AM
Abstract :
Using the Utah scatter phantom with media of different densities and activity proportions, the authors tested the accuracy of quantitation in the two-dimensional (2-D) and three-dimensional (3-D) modes of acquisition of the ECAT EXACT HR+ tomograph. The influence of radioactive sources outside the field of view (FOV) was also investigated, using different bed positions. The authors measured the activities in regions of interest drawn in the reconstructed images and compared the means through several planes versus the activities expected from well counter measurements. The 3-D scatter correction algorithm successfully restored the activity concentration in the various chambers of the phantom, with relative errors between -10.4 and +12.0%, slightly larger than those observed in 2-D (-8.6 to +5.6%) but similar to values when no activity was out of the FOV (between +4.0 and +4.6%). The activity out of the FOV increased the relative errors and introduced nonuniformities along the axial direction. The attenuation coefficient of the different materials also influenced the results: negative activity values were observed for high attenuation coefficient regions of the 3-D scatter corrected images
Keywords :
medical image processing; positron emission tomography; radioactive sources; 3-D PET quantitation; 3-D scatter corrected images; 3-D scatter correction algorithm; ECAT EXACT HR+ tomograph; activity concentration; attenuating media; axial direction; high attenuation coefficient regions; medical diagnostic imaging; nuclear medicine; out of the field of view radioactive sources; phantom; relative errors; well counter measurements; Attenuation; Counting circuits; Error correction; Image reconstruction; Image restoration; Imaging phantoms; Positron emission tomography; Scattering; Testing; Two dimensional displays;
Journal_Title :
Nuclear Science, IEEE Transactions on