Title :
The Integration of Biological Pathway Knowledge in Cancer Genomics: A review of existing computational approaches
Author :
Varadan, Vinay ; Mittal, Prateek ; Vaske, Charles J. ; Benz, Stephen C.
Abstract :
We review existing computational approaches for the integration of cancer genomic data with regulatory mechanisms represented in biological pathway databases and suggest opportunities for the signal processing community to contribute to this exciting field.
Keywords :
cancer; genomics; biological pathway database; biological pathway knowledge; cancer genomic data; computational approach; signal processing community; Biological cells; Cancer; Cells (biology); Diseases; Genetics; Genomics; Molecular biophysics; Proteomics;
Journal_Title :
Signal Processing Magazine, IEEE
DOI :
10.1109/MSP.2011.943037
