• DocumentCode
    1427872
  • Title

    Synthesizing Distributions of Magnetic Nanoparticles for Clinical Hyperthermia

  • Author

    Barba, Paolo Di ; Dughiero, Fabrizio ; Sieni, Elisabetta

  • Author_Institution
    Dept. of Electr. Eng., Univ. of Pavia, Pavia, Italy
  • Volume
    48
  • Issue
    2
  • fYear
    2012
  • Firstpage
    263
  • Lastpage
    266
  • Abstract
    An automated procedure based on evolutionary computation and Finite Element Analysis (FEA) is proposed to synthesize the optimal distribution of nanoparticles (NPs) in multi-site injection for a Magnetic Fluid Hyperthermia (MFH) therapy. In particular a bi-objective formulation of the synthesis problem is considered taking into account both surface and volume temperature distribution in the tumor region.
  • Keywords
    finite element analysis; hyperthermia; magnetic fluids; magnetic particles; nanomagnetics; nanomedicine; nanoparticles; radiation therapy; tumours; FEA; clinical hyperthermia; finite element analysis; magnetic fluid hyperthermia therapy; magnetic nanoparticles; multisite injection; tumor region; volume temperature distribution; Heating; Hyperthermia; Magnetic resonance imaging; Nanoparticles; Optimization; Temperature distribution; Tumors; Finite-element field analysis; magnetic fluid hyperthermia; magnetic nanoparticles; optimization;
  • fLanguage
    English
  • Journal_Title
    Magnetics, IEEE Transactions on
  • Publisher
    ieee
  • ISSN
    0018-9464
  • Type

    jour

  • DOI
    10.1109/TMAG.2011.2174340
  • Filename
    6136564