The inverse problem in electroneurography. II. Computational aspects and evaluation using simulated data

(For pt.1 see ibid., vol.35, no.10, p.769-77, 1988). Theoretical concepts of a technique for the estimation of fiber velocity distributions from compound nerve action potentials are illustrated using simulated compound action potential (CAP) data. After a concise summary of the estimation formalism, the numerical implementation of the procedure is given followed by the elaboration of a number of aspects of a practical nature. It is shown that reliable estimates of both fast and slow fiber distributions can be derived. The sensitivity of the procedure to various possible error sources is investigated. It is seen that many factors can be dealt with, properly including recording noise and incorrect determination of recording distance. Possible branching of the nerve can also be traced. A correct description of the amplitude and the waveshape of the single-fiber action potentials appears to be the most critical factor in a practical application.