Title :
Two-dimensional FDTD analysis of a pulsed microwave confocal system for breast cancer detection: fixed-focus and antenna-array sensors
Author :
Hagness, Susan C. ; Taflove, Allen ; Bridges, Jack E.
Author_Institution :
Dept. of Electr. & Comput. Eng., Wisconsin Univ., Madison, WI, USA
Abstract :
A novel focused active microwave system is investigated for detecting tumors in the breast. In contrast to X-ray and ultrasound modalities, the method reviewed here exploits the breast-tissue physical properties unique to the microwave spectrum, namely, the translucent nature of normal breast tissues and the high dielectric contrast between malignant tumors and surrounding lesion-free normal breast tissues. The system uses a pulsed confocal technique and time-gating to enhance the detection of tumors while suppressing the effects of tissue heterogeneity and absorption. Using published data for the dielectric properties of normal breast tissues and malignant tumors, the authors have conducted a two-dimensional (2-D) finite-difference time-domain (FDTD) computational electromagnetics analysis of the system. The FDTD simulations showed that tumors as small as 2 mm in diameter could be robustly detected in the presence of the background clutter generated by the heterogeneity of the surrounding normal tissue. Lateral spatial resolution of the tumor location was found to be about 0.5 cm.
Keywords :
biomedical equipment; biomedical imaging; cancer; finite difference time-domain analysis; mammography; microwave antenna arrays; microwave imaging; 2 mm; antenna-array sensors; background clutter; biomedical electromagnetic imaging; breast cancer detection; breast tumors detection; computational electromagnetics analysis; fixed-focus sensors; lateral spatial resolution; medical diagnostic imaging; pulsed microwave confocal system; surrounding normal tissue heterogeneity; two-dimensional FDTD analysis; Breast cancer; Breast neoplasms; Breast tissue; Cancer detection; Dielectrics; Finite difference methods; Microwave antennas; Microwave sensors; Sensor systems; Time domain analysis; Breast; Breast Neoplasms; Computer Simulation; Electromagnetics; Female; Humans; Microscopy, Confocal; Microwaves; Signal Processing, Computer-Assisted;
Journal_Title :
Biomedical Engineering, IEEE Transactions on