Title :
Encapsulation of CdTe quantum dots in polyvinylpyrrolidone nanoparticle for live cell imaging
Author_Institution :
State Key Lab. of Food Sci. & Technol., Jiangnan Univ., Wuxi, China
Abstract :
Highly luminescent and water-soluble CdTe quantum dots encapsulated in polyvinylpyrrolidone nanoparticles (QDs/PNs) have been synthesised by one-pot aqueous route. Fluorescence of the as-prepared QDs/PNs was tunable from 539 to 606 nm and photoluminescent quantum yield could reach up to 47%. High quality of QDs/PNs was also observed by narrow full-width at half-maximum as small as 36 nm in the fluorescence spectra. Using fluorescence microscopy, we demonstrated uptake of QDs/PNs by 293 T human renal epithelial cells. Our results suggest that such nanoparticles are potentially powerful tools for fluorescent gene delivery reagent.
Keywords :
II-VI semiconductors; biological techniques; cadmium compounds; cellular biophysics; encapsulation; fluorescence; nanobiotechnology; nanofabrication; nanoparticles; optical microscopy; photoluminescence; polymers; semiconductor quantum dots; CdTe; encapsulation; fluorescence microscopy; fluorescence spectra; fluorescent gene delivery reagent; full-width at half-maximum; highly luminescent quantum dots; human renal epithelial cells; live cell imaging; magnetic flux density 293 T; one-pot aqueous route; photoluminescent quantum yield; polyvinylpyrrolidone nanoparticles; water-soluble quantum dots;
Journal_Title :
Micro & Nano Letters, IET
DOI :
10.1049/mnl.2011.0551
