Lack of effects on heart rate and blood pressure in ketamine-anesthetized rats briefly exposed to ultra-wideband electromagnetic pulses

Author

Jauchem, James R. ; Frei, Melvin R. ; Ryan, Kathy L. ; Merritt, James H. ; Murphy, Michael R.

Author_Institution

Res. Lab., Brooks AFB, TX, USA

Volume

46

Issue

1

fYear

1999

Firstpage

117

Lastpage

120

Abstract

Fourteen Sprague-Dawley rats were exposed to pulses produced by a Bournlea ultra-wideband (UWB) pulse generator (rise time, 318-337 ps; maximum E field, 19-21 kV/m). Exposures at a repetition frequency of 1 kHz for 0.5 s or to repetitive pulse trains (2-s exposure periods alternating with 2 s of no exposure, for a total of 2 min) resulted in no significant changes in heart rate or mean arterial blood pressure. These results suggest that acute whole-body exposure to UWB pulses does not have a detrimental effect on the cardiovascular system.

Keywords

biological effects of microwaves; electrocardiography; haemodynamics; 0.5 s; 1 kHz; 2 min; 2 s; 318 to 337 ps; Bournlea ultra-wideband pulse generator; Sprague-Dawley rats; cardiovascular system; heart rate; ketamine-anesthetized rats; mean arterial blood pressure; radiation biology; repetition frequency; ultra-wideband electromagnetic pulses; Blood pressure; EMP radiation effects; Electromagnetic fields; Electromagnetic forces; Heart rate; Laboratories; Pulse generation; Radio frequency; Rats; Ultra wideband technology; Anesthetics, Dissociative; Animals; Blood Pressure; Electromagnetic Fields; Heart Rate; Ketamine; Male; Rats; Rats, Sprague-Dawley;

fLanguage

English

Journal_Title

Biomedical Engineering, IEEE Transactions on

Publisher

ieee

ISSN

0018-9294

Type

jour

DOI

10.1109/10.736767

Filename

736767