DocumentCode
15703
Title
Rapid electronic prediction of gene expression regulation in bacterial cells
Author
Alam, Shahinur ; Lai, E.M.-K. ; Young, James ; Hasan, S. M. Rezaul
Author_Institution
Sch. of Eng. & Adv. Technol., Massey Univ., Auckland, New Zealand
Volume
50
Issue
22
fYear
2014
fDate
10 23 2014
Firstpage
1566
Lastpage
1568
Abstract
A cytomorphic circuit that can mimic gene expression regulation mechanisms is presented. It is shown that this circuit can efficiently predict the cellular response of the bacterium Escherichia coli in real time. The simulation outputs of the circuit are compared with biological experimental results. The significant similarity between these results shows that the circuit can be used to predict cellular malfunctioning within microseconds.
Keywords
cellular biophysics; genetics; microorganisms; Escherichia coli bacterium; bacterial cells; cellular malfunctioning; cellular response; cytomorphic circuit; gene expression regulation; microseconds; rapid electronic prediction; real time;
fLanguage
English
Journal_Title
Electronics Letters
Publisher
iet
ISSN
0013-5194
Type
jour
DOI
10.1049/el.2014.2144
Filename
6937285
Link To Document