A simple Computational Model-Based Validation of Guyton´s closed circuit analysis of the heart and the peripheral circulatory system

Author

Zervides, C. ; Hose, D.R.

Author_Institution

Dept. of Medical Phys. & Clinical Eng., Sheffield Univ.

fYear

2006

Firstpage

5486

Lastpage

5489

Abstract

A computer model of the human cardiovascular system has been created based on Guyton´s closed circuit analysis of the heart and the peripheral circulatory system. This model was checked against Guyton´s experiments performed in anesthetised dogs regarding the normal venous return curve, the effect of mean circulatory filling pressure (MCFP) and the importance of arterial venous and capillary resistance. These comparisons indicate that this simple model is valid for the study of Guyton´s experimental work and also forms the bases of a more complex model of the cardiovascular model with specific attention to the venous system

Keywords

blood vessels; cardiovascular system; haemodynamics; physiological models; Guyton closed circuit analysis; anesthetised dogs; artery; capillary resistance; computational model-based validation; heart; human cardiovascular system; mean circulatory filling pressure; normal venous return curve; peripheral circulatory system; Cardiovascular system; Circuit analysis computing; Circulatory system; Computational modeling; Computer peripherals; Dogs; Filling; Heart; Humans; Immune system;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the

Conference_Location

Shanghai

Print_ISBN

0-7803-8741-4

Type

conf

DOI

10.1109/IEMBS.2005.1615725

Filename

1615725