Title :
Optimization of Bulk and Surface Biosensing in Plane Stratified Configurations
Author :
Razansky, D. ; Einziger, P.D. ; Adam, D.R.
Author_Institution :
Dept. of Biomed. Eng., Technion-Israel Inst. of Technol., Haifa
Abstract :
Various biochemical and tissue sensors utilize layered configurations to accurately measure the physical parameters (e.g. refractive index) of the suspension or tissue under investigation. The most sensitive techniques, like these based on well-known surface plasmon resonance (SPR) phenomenon, are usually limited to surface sensing at the infrared and light wavelength bands. We present a new type of broadband absorption biosensing method, which utilizes lossy resonance modes (LRM) in thin lossy film configurations and can be facilitated in a highly scalable and sensitive manner for both bulk and surface sensing in various frequency bands, from radio to light frequencies
Keywords :
biochemistry; biological techniques; biological tissues; biomedical measurement; chemical sensors; infrared detectors; optical films; optical losses; optical sensors; surface plasmon resonance; suspensions; thin films; biochemical sensor; biological tissue; broadband absorption biosensing; bulk biosensing; infrared sensing; light wavelength bands; lossy film configurations; lossy resonance modes; plane stratified configurations; surface biosensing; surface plasmon resonance; suspension; tissue sensor; Biomedical measurements; Biosensors; Electromagnetic wave absorption; Frequency; Optical films; Plasmons; Refractive index; Resonance; Surface waves; Wavelength measurement;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1616840