Title :
Surface Modification of Bio-MEMS Micro-device with Conducting Polymer - Studies with Rat Cardiomyocytes
Author :
Lin, Chii-Wann ; Lee, Ming-Fung ; Yang, Yi-Fan ; Wu, Chau-Chung
Author_Institution :
Inst. of Biomed Eng., Nat. Taiwan Univ., Taipei
Abstract :
Conducting polymer can modify device surface properties and incorporate biomolecules for immobilization by electropolymerization at the same time. We investigated a method for surface modification by electrochemically deposited polypyrrole onto surface of bio-MEMS micro device. We reported the effects of the numbers of CV cycle on the deposited film thickness and roughness in this paper. Furthermore, to prepare polypyrrole entrapment biomolecules on micro-device as a cell-culture substrate was demonstrated to promote cells adhesion
Keywords :
bioMEMS; biosensors; cardiology; cellular biophysics; conducting polymers; microelectrodes; molecular biophysics; polymerisation; surface roughness; surface treatment; Au; CV cycle; bioMEMS microdevice; cell adhesion; cell-culture substrate; conducting polymer; device surface properties; electrochemically deposited polypyrrole; electropolymerization; film roughness; film thickness; polypyrrole entrapment biomolecules; rat cardiomyocytes; surface modification; Adhesives; Biosensors; Cardiology; Electrodes; Gold; Microelectrodes; Molecular biophysics; Polymers; Rough surfaces; Surface roughness; biomolecules; cell adhesion; electropolymerization; micro electrode; polypyrrole;
Conference_Titel :
Engineering in Medicine and Biology Society, 2005. IEEE-EMBS 2005. 27th Annual International Conference of the
Conference_Location :
Shanghai
Print_ISBN :
0-7803-8741-4
DOI :
10.1109/IEMBS.2005.1617006
