Title :
Investigation on the Properties of Group II Introns for Potential Gene Therapy
Author :
Mao, Shuhong ; Jin, Genming ; Wei, Zengquan ; Xie, Hongmei
Author_Institution :
Tianjin Key Lab. of Ind. Microbiol., Tianjin Univ. of Sci. & Technol., Tianjin
Abstract :
Group II introns, found in bacterial genones and organelles of eukaryotes, are potential tools in genetic engineering and genomic analysis. The new properties of group II introns were first explored by ionizing radiation giving rise to multiple cellular and biological effects. Experimental results showed that group II introns can be effective vectors in gene therapy.
Keywords :
cellular biophysics; genetics; microorganisms; patient treatment; bacterial genones; eukaryotes; gene therapy; genetic engineering; genomic analysis; group II introns; ionizing radiation; organelles; Bioinformatics; Capacitive sensors; DNA; Gene therapy; Genetic engineering; Genomics; Ionizing radiation; Laboratories; Microorganisms; Sequences;
Conference_Titel :
Bioinformatics and Biomedical Engineering, 2008. ICBBE 2008. The 2nd International Conference on
Conference_Location :
Shanghai
Print_ISBN :
978-1-4244-1747-6
Electronic_ISBN :
978-1-4244-1748-3
DOI :
10.1109/ICBBE.2008.88