DocumentCode :
1660922
Title :
Biochemical allosteric modeling for creating new electronic signal transmission system under the time minimum optimization
Author :
Hirayama, H. ; Okita, Y. ; Nishimura, T.
Author_Institution :
Dept. of Public Health, Asahikawa Med. Coll., Japan
Volume :
2
fYear :
1999
fDate :
6/21/1905 12:00:00 AM
Firstpage :
383
Abstract :
We proposed a new theoretical circuit which is based on the multiple phase complex biochemical reaction circuit under the time minimum optimal control principle. The circuit is characterized by an allosteric enzyme, the conformation of which changes depending on the number of bound substrates. As the number of enzyme bound substrates increases, the structure of the enzyme changes successively. Then, the affinities of residual subunits are potentiated. The present application and modeling of an allosteric circuit will be applicable for creating a new electronic circuit and its evaluation
Keywords :
biochemistry; bioelectric phenomena; biomolecular electronics; molecular biophysics; optimal control; optimisation; proteins; allosteric circuit; allosteric enzyme; biochemical allosteric modeling; electronic signal transmission system; enzyme bound substrates; multiple phase complex biochemical reaction circuit; residual subunit affinity; theoretical circuit; time minimum optimal control principle; time minimum optimization; Biochemistry; Biological control systems; Circuits; Educational institutions; Inhibitors; Optimal control; Postal services; Public healthcare;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Systems, Man, and Cybernetics, 1999. IEEE SMC '99 Conference Proceedings. 1999 IEEE International Conference on
Conference_Location :
Tokyo
ISSN :
1062-922X
Print_ISBN :
0-7803-5731-0
Type :
conf
DOI :
10.1109/ICSMC.1999.825289
Filename :
825289
Link To Document :
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