Forward solution of chaotic myocardial activation

This study deals with a mathematical model of the cellular action potential with its underlying ionic currents in human myocardium based upon the Luo-Rudy phase II cell model. The activation process is calculated within a three dimensional heart model, taking into account the behaviour of each single cell membrane. The propagation is simulated using the Finite Difference Method in the time domain. The potentials simulated on the epicardium are mapped into a finite element model of the human torso. 300 sources on the heart surface are calculated forward. These simulations give an idea how different kinds of arrhythmias look like in multi channel electrocardiograms, and are therefore a helpful diagnostic tool for analysing cardiac arrhythmias. The authors use these simulations, for example, for testing their algorithms to find the solution of the inverse problem of electrocardiography