Estimation algorithm of Butyrylcholinesterase for cirrhosis using instance-based reasoning

An estimation algorithm for Butyrylcholinesterase (BChE) in Kochi Medical School Hospital is proposed for early prediction of cirrhosis. It provides automatic calculation of similarity of input BChE for known learning data constructed by neural network, which estimates subsequent value of input value based on instance-based reasoning. Experimental estimation results for real data show that mean difference of day under normal values for estimated value is 178 in 4320 interval compared with true data and that the proposed algorithm distinguish cirrhosis patients from other patients. The proposed algorithm constructs learning database automatically and provides early prediction using screening study in hospital.