Continuous paramagnetophoretic microseparator for blood cells

Author

Ki-Ho Han ; Landers, J.P. ; Frazier, A.B.

Author_Institution

Sch. of Electr. & Comput. Eng., Georgia Inst. of Technol., Atlanta, GA, USA

Volume

2

fYear

2003

Firstpage

1229

Abstract

This paper presents a continuous paramagnetophoretic (PMP) microseparator for directly separating blood cells from whole blood by using a high gradient magnetic separation (HGMS) method. For high magnetic separation force, the present PMP separator is fabricated by microfabrication technology, and directly separates red and white blood cells from whole blood based on their magnetic properties. The theoretical model of the PMP microseparator is derived, and simulated values are compared with calculated values. A quantitative analysis using a hemocytometer shows that 92% of red blood cells are separated from whole blood by the present PMP microseparator.

Keywords

biomagnetism; blood; magnetic forces; magnetic separation; micromechanical devices; blood cell separation; continuous paramagnetophoretic microseparator; hemocytometer; high gradient magnetic separation method; magnetic properties; magnetic separation force; microfabrication technology; red blood cells; white blood cells; Cells (biology); Magnetic analysis; Magnetic fields; Magnetic particles; Magnetic separation; Magnetostatics; Particle separators; Portable media players; Red blood cells; Wire;

fLanguage

English

Publisher

ieee

Conference_Titel

TRANSDUCERS, Solid-State Sensors, Actuators and Microsystems, 12th International Conference on, 2003

Conference_Location

Boston, MA, USA

Print_ISBN

0-7803-7731-1

Type

conf

DOI

10.1109/SENSOR.2003.1216994

Filename

1216994