• DocumentCode
    1735120
  • Title

    Protein Local Tertiary Structure Prediction Using the Adaptively-Branching FGK-DF Model

  • Author

    Chen, Bing ; Hudson, Cody ; Crawford, Aaron ; MinWoo Kim

  • Author_Institution
    Dept. of Comput. Sci., Univ. of Central Arkansas, Conway, AR, USA
  • Volume
    1
  • fYear
    2013
  • Firstpage
    378
  • Lastpage
    381
  • Abstract
    For the past twenty years, protein tertiary structure research has been given much attention. Unfortunately, each approach has significant shortcomings, such as necessary time, capital, or restrictions imposed by the method, limiting the resolution or novelty of produced tertiary structures. This work proposes the Adaptively-Branching Fuzzy Greedy K-means-Decision Forest (FGK-DF) model, which utilizes conserved sequential and structural motifs that transcend protein family boundaries, to predict the local tertiary structure of proteins with unknown structures.
  • Keywords
    biology computing; fuzzy set theory; greedy algorithms; molecular biophysics; proteins; adaptively-branching FGK-DF model; adaptively-branching fuzzy greedy k-means-decision forest model; conserved sequential motif; produced tertiary structures; protein family boundary; protein local tertiary structure prediction; protein tertiary structure research; structural motif; Adaptation models; Decision trees; Hidden Markov models; Predictive models; Proteins; Training; Vegetation; Adaptive Branch; Decision Forest; FGK Model;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Machine Learning and Applications (ICMLA), 2013 12th International Conference on
  • Conference_Location
    Miami, FL
  • Type

    conf

  • DOI
    10.1109/ICMLA.2013.77
  • Filename
    6784647