DocumentCode :
1751809
Title :
A three dimensional growth model for primary cancer
Author :
Flores-Ascencio, Sabas ; Perez-Meana, Hector ; Nakano-Miyatake, Mariko
Author_Institution :
Nat. Polytech. Inst., Mexico City, Mexico
Volume :
1
fYear :
2001
fDate :
2001
Firstpage :
241
Abstract :
Maybe the most aggressive phenomena in biology is the growth of cancer cells. In this paper we propose a simple three-dimensional model to simulate the growth of carcinoma, which includes cell proliferation, reciprocal influence among cells, cell division and cell death. Every simulated pattern growth is characterized by its gyration radius, number of cells on tumor periphery and fractal dimension. We use the DLA model and computer simulation to characterized the growth phenomenon. The Application of DLA (diffusion-limited aggregation) model to generate fractal structure is shown in this work. The similarity between this computational model and some abnormal cell growth, are shown as well. We use a hash function for the DLA in three-dimensional problem; the possibility of developing studies in higher dimensions without affecting the required time of the algorithm is shown. Also, a comparison between the simulated patterns and explants of primary tumors is done
Keywords :
aggregation; cancer; cellular biophysics; fractals; physiological models; tumours; DLA model; cancer cell growth; carcinoma; cell death; cell division; cell proliferation; computational model; diffusion-limited aggregation; explants; fractal dimension; gyration radius; hash function; primary cancer; simulated pattern growth; simulated patterns; three dimensional growth model; tumor periphery; Aggregates; Biological system modeling; Cancer; Cells (biology); Computational modeling; Computer simulation; Fractals; Lattices; Lesions; Neoplasms;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Physics and Engineering of Millimeter and Sub-Millimeter Waves, 2001. The Fourth International Kharkov Symposium on
Conference_Location :
Kharkov
Print_ISBN :
0-7803-6473-2
Type :
conf
DOI :
10.1109/MSMW.2001.946811
Filename :
946811
Link To Document :
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