• DocumentCode
    1785220
  • Title

    Drug resistance gene identification algorithm for next-generation sequencing data

  • Author

    Guan-Jie Hua ; Che-Lun Hung ; Chuan Yi Tang ; Huiru Zheng

  • Author_Institution
    Dept. Comput. Sci., Nat. Tsing Hua Univ., Hsinchu, Taiwan
  • fYear
    2014
  • fDate
    2-5 Nov. 2014
  • Firstpage
    17
  • Lastpage
    21
  • Abstract
    In the 21st century, antibiotic resistance has become a crucial and growing phenomenon in contemporary medicine. Multidrug resistant leads that antibiotics cannot be used to treat infections. In this paper, we propose a novel and efficient method to identify drug resistance genes from raw reads produced by next generation sequencing technology for metagenomes. The experimental results show that the proposed method is able to identify the resistance genes of Acinetobacter baumannii, TYTH-1.
  • Keywords
    bioinformatics; drugs; genetics; genomics; microorganisms; Acinetobacter baumannii TYTH-1; antibiotic resistance; contemporary medicine; drug resistance gene identification algorithm; infections; metagenomes; multidrug resistance; next-generation sequencing data; Antibiotics; Bioinformatics; DNA; Databases; Immune system; Microorganisms; Sequential analysis; Assembly; Drug Resistance; Integron; Metagenomics; Next Generation Sequencing;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioinformatics and Biomedicine (BIBM), 2014 IEEE International Conference on
  • Conference_Location
    Belfast
  • Type

    conf

  • DOI
    10.1109/BIBM.2014.6999381
  • Filename
    6999381