DocumentCode
1785220
Title
Drug resistance gene identification algorithm for next-generation sequencing data
Author
Guan-Jie Hua ; Che-Lun Hung ; Chuan Yi Tang ; Huiru Zheng
Author_Institution
Dept. Comput. Sci., Nat. Tsing Hua Univ., Hsinchu, Taiwan
fYear
2014
fDate
2-5 Nov. 2014
Firstpage
17
Lastpage
21
Abstract
In the 21st century, antibiotic resistance has become a crucial and growing phenomenon in contemporary medicine. Multidrug resistant leads that antibiotics cannot be used to treat infections. In this paper, we propose a novel and efficient method to identify drug resistance genes from raw reads produced by next generation sequencing technology for metagenomes. The experimental results show that the proposed method is able to identify the resistance genes of Acinetobacter baumannii, TYTH-1.
Keywords
bioinformatics; drugs; genetics; genomics; microorganisms; Acinetobacter baumannii TYTH-1; antibiotic resistance; contemporary medicine; drug resistance gene identification algorithm; infections; metagenomes; multidrug resistance; next-generation sequencing data; Antibiotics; Bioinformatics; DNA; Databases; Immune system; Microorganisms; Sequential analysis; Assembly; Drug Resistance; Integron; Metagenomics; Next Generation Sequencing;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedicine (BIBM), 2014 IEEE International Conference on
Conference_Location
Belfast
Type
conf
DOI
10.1109/BIBM.2014.6999381
Filename
6999381
Link To Document