Neuromodulation with subthreshold electrical stimulation: Mechanisms, safety, and seeking proof of effectiveness

Most of the information integration in the central nervous system involves subthreshold events that involve biochemical changes that result in electrical changes. This information through electrical modulation is integrated temporally and spatially to cause or alter the rate of nerve impulses (action potentials). The talk by Dr. Krauthamer will be in three parts. The first will outline some of the physiological mechanisms used by devices to modulate neural function with electrical stimulation from DC to kilohertz. The second will discuss some of the research on assessing safety. The third will discuss the quest to demonstrate efficacy.