Title :
Collective rhythms of multicellular systems by using impulsive control strategy
Author :
Yonghui Sun ; Lulu Wang ; Yue Tu
Author_Institution :
Coll. of Energy & Electr. Eng., Hohai Univ., Nanjing, China
Abstract :
This paper considers the collective rhythms of multicellular systems by using partial impulsive control approach. The main aim is to design an impulsive controller based on only those partially measurable cell states, so that the collective rhythms can be achieved for the multicellular systems with cell-to-cell communication mechanism. Based on the Lyapunov stability theory, several sufficient conditions are derived to achieve the collective rhythms of multicellular systems. Finally, a synthetic multicellular system with simulation results is included to validate the developed results.
Keywords :
Lyapunov methods; biocontrol; cellular biophysics; control system synthesis; stability; Lyapunov stability theory; cell-to-cell communication mechanism; collective rhythms; impulsive controller design; partial impulsive control approach; partially measurable cell states; sufficient conditions; synthetic multicellular system; Couplings; Genetics; Heart beat; Lyapunov methods; Oscillators; Synchronization; Collective rhythms; cell-to-cell communication mechanism; impulsive control; multicellular systems;
Conference_Titel :
Control Conference (CCC), 2013 32nd Chinese
Conference_Location :
Xi´an