Title :
A multi-modality system for dynamic imaging of cancer
Author :
Gulsen, G. ; Unlu, M.B. ; Birgul, O. ; Yan, H. ; Nalcioglu, O.
Author_Institution :
Tu & Yuen Center for Functional Onco-Imaging, California Univ., Irvine, CA
Abstract :
In the present work, the details of a combined MR-diffuse optical imaging system for dynamic contrast enhanced imaging of cancer are given. As a part of this effort, a multi-spectral diffuse optical tomography system was integrated with an MRI system. The integration of the optical imaging system with the 4T MRI system was realized by incorporating a fiber adaptive interface inside the MR magnet. Coregistration was achieved by a special probe design utilizing fiducial markers. A dynamic phantom was developed and used to test the performance of the system. Human and animal studies are currently being undertaken to assess the performance of the system in-vivo
Keywords :
biomedical MRI; biomedical optical imaging; cancer; image registration; medical image processing; optical tomography; phantoms; 4 T; MR system; cancer; dynamic contrast enhanced imaging; dynamic phantom; fiber adaptive interface; fiducial markers; image coregistration; multimodality system; multispectral diffuse optical tomography system; Cancer; Imaging phantoms; Integrated optics; Magnetic cores; Magnetic resonance imaging; Optical fiber testing; Optical imaging; Probes; System testing; Tomography;
Conference_Titel :
Biomedical Imaging: Nano to Macro, 2006. 3rd IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
0-7803-9576-X
DOI :
10.1109/ISBI.2006.1625005
