Title :
Robust statistics for nonparametric group analysis in fMRI
Author :
Mériaux, Sébastien ; Roche, Alexis ; Thirion, Bertrand ; Dehaene-Lambertz, Ghislaine
Author_Institution :
Service Hospitalier Frederic Joliot, CEA, Orsay
Abstract :
In order to deal with inhomogeneous groups of subjects in fMRI studies, we investigate several robust statistics to perform random-effect analysis on the mean population effect (sign statistic, Wilcoxon´s signed rank statistic and empirical t statistic). The tests´ significance levels are calibrated using the same sign permutation framework, allowing for exact specificity control under a mild symmetry assumption about the subjects´ distribution. The benefit of the robust approach is illustrated on a speech listening experiment involving three month-old infants
Keywords :
biomedical MRI; medical image processing; nonparametric statistics; paediatrics; statistical analysis; Wilcoxon signed rank statistic; empirical t statistic; exact specificity control; fMRI; infants; mean population effect; mild symmetry assumption; nonparametric group analysis; random-effect analysis; robust statistics; sign permutation framework; sign statistic; speech listening; Image analysis; Pediatrics; Performance analysis; Robustness; Speech analysis; Statistical analysis; Statistical distributions; Statistics; Tellurium; Testing;
Conference_Titel :
Biomedical Imaging: Nano to Macro, 2006. 3rd IEEE International Symposium on
Conference_Location :
Arlington, VA
Print_ISBN :
0-7803-9576-X
DOI :
10.1109/ISBI.2006.1625073