Title :
A tissue-level model of the left ventricle for the analysis of regional myocardial function
Author :
Le Rolle, V. ; Hernandez, A.I. ; Richard, P.-Y. ; Donal, E. ; Carrault, G.
Author_Institution :
INSERM U642, Rennes
Abstract :
This paper presents a model-based method for the analysis of regional myocardial strain, based on echocardiography and Tissue Doppler Imaging (TDI). A multi- formalism, tissue-level electromechanical model of the left ventricle is proposed. The parameters of the model are identified in order to reproduce regional strain signal morphologies obtained from a healthy subject and a patient presenting a dilated cardiomyopathy. The parameters identified for the DCM patient allow the localization of the failing myocardial segments and may be useful for a better design of cardiac resynchronization therapy on heart failure patients.
Keywords :
biological tissues; biomechanics; diseases; echocardiography; TDI; cardiac resynchronization therapy; dilated cardiomyopathy; echocardiography; heart failure patients; left ventricle; multiformalism tissue-level electromechanical model; regional myocardial function; regional myocardial strain; tissue Doppler imaging; tissue-level model; Capacitive sensors; Cardiology; Heart; Microscopy; Morphology; Myocardium; Pathology; Performance evaluation; Signal analysis; Signal processing; Algorithms; Computer Simulation; Echocardiography; Elasticity; Elasticity Imaging Techniques; Humans; Image Interpretation, Computer-Assisted; Imaging, Three-Dimensional; Models, Cardiovascular; Reproducibility of Results; Sensitivity and Specificity; Stress, Mechanical; Ventricular Dysfunction, Left;
Conference_Titel :
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE
Conference_Location :
Lyon
Print_ISBN :
978-1-4244-0787-3
DOI :
10.1109/IEMBS.2007.4352505
