Title :
Branching medial models for cardiac shape representation
Author :
Sun, Hui ; Avants, Brian B. ; Frangi, Alejandro F. ; Ordas, Sebastian ; Gee, James C. ; Yushkevich, Paul A.
Author_Institution :
Depts. of Radiol., Univ. of Pennsylvania, Philadelphia, PA
Abstract :
The cm-rep (continuous medial representation) is a powerful shape representation method that models a 3D object by describing its medial axis (skeleton) and boundary as continuous parametric manifolds. It provides parametrization of the entire interior of the object, which can be used for combined statistical analysis of shape and appearance. This paper extends the cm-rep to more complex shapes with multi-figures, i.e., shapes whose skeletons have branches. Along the branching curves, the equality constraints enforced by the medial geometry are implemented as soft penalties in the deformable model. The remaining small violations are corrected by local adjustments. As a proof of concept, the branching continuous medial representation is applied to a 2-chamber heart model data set consisting of 428 cardiac shapes from 90 subjects. The results show that our model can capture the heart shape accurately.
Keywords :
biomedical MRI; cardiology; geometry; image representation; medical image processing; shape measurement; statistical analysis; 2-chamber heart model data set; 3D object model; MRI; branching medial models; cardiac shape representation; cardiac thickness analysis; combined statistical analysis; continuous medial representation; continuous parametric manifolds; deformable model; medial geometry; medical imaging analysis; soft penalties; Communications technology; Fingers; Heart; Image analysis; Information geometry; Pediatrics; Radiology; Shape; Skeleton; Solid modeling; 2-chamber heart model; Branching Medial Model; Cardiac Thickness Analysis; Medial Axis;
Conference_Titel :
Biomedical Imaging: From Nano to Macro, 2008. ISBI 2008. 5th IEEE International Symposium on
Conference_Location :
Paris
Print_ISBN :
978-1-4244-2002-5
Electronic_ISBN :
978-1-4244-2003-2
DOI :
10.1109/ISBI.2008.4541289