Title :
Parsimonious Design Principles for Motor Unit Models
Author :
Lan Ban ; Shapiro, N.P. ; Lee, R.H.
Author_Institution :
Georgia Inst. of Technol., Atlanta
Abstract :
Motor units are known to display type-specific differences in passive and active electrical properties, and attempts to predict motor unit type based on the measurement of membrane properties have been rather successful. Quantitative models of motoneurons have also grown in complexity and their predictive power is predicated upon the accurate description of basic membrane properties. This paper presents results from a modeling study which sought to specify a small and simple set of ";design rules"; that motoneurons might obey during type-specific differentiation.
Keywords :
bioelectric phenomena; biomembranes; cellular biophysics; neurophysiology; physiological models; design rules; electrical properties; membrane properties; motoneurons; motor unit models; parsimonious design; type-specific differentiation; Analytical models; Biomedical engineering; Biomembranes; Computational modeling; Displays; Electric variables measurement; Immune system; Predictive models; Recruitment; Surface resistance; Algorithms; Cations; Cell Differentiation; Cell Membrane; Dendrites; Equipment Design; Humans; Models, Neurological; Models, Statistical; Models, Theoretical; Motor Neurons; Movement; Potassium Channels; Sodium Channels; Time Factors;
Conference_Titel :
Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE
Conference_Location :
Lyon
Print_ISBN :
978-1-4244-0787-3
DOI :
10.1109/IEMBS.2007.4352814
