PCB/Polymer based micro-fluidic system for NMR Spectroscopy for nanoliters sample volume

Author

Pasquet, G. ; Chateaux, J.-F. ; Deman, A.-L. ; Morin, P. ; Fenet, B.

Author_Institution

Univ. Claude Bernard, Villeurbanne

fYear

2007

fDate

22-26 Aug. 2007

Firstpage

2968

Lastpage

2971

Abstract

In this work, we report on the realization of an innovating micro system for NMR spectroscopy on small sample volume (30-100 nL). We propose a micro system based on Printed Circuit Board (PCB) technology for the NMR probe associated to a micro fluidic system made with polymer (COC). The comparison of several samples during the same NMR experiments could provide more precise information. In that context, we have realized a micro-fluidic system with two cavities, each cavity presenting a volume of 37 nl. The fabrication process is described, and first results are reported. The tight sealing of the micro-fluidic system has been demonstrated and preliminary NMR experiment results are presented.

Keywords

NMR spectroscopy; microfluidics; polymers; printed circuits; spectrochemical analysis; NMR spectroscopy; PCB-polymer based microfluidic system; fabrication process; microcavity; nanoliters sample volume; printed circuit board technology; tight sealing; Chemicals; Coils; Fabrication; Fluidic microsystems; Microfluidics; Nuclear magnetic resonance; Polymers; Printed circuits; Signal to noise ratio; Spectroscopy; Computer-Aided Design; Equipment Design; Equipment Failure Analysis; Magnetic Resonance Spectroscopy; Magnetics; Microchemistry; Microfluidic Analytical Techniques; Nanotechnology; Polycarboxylate Cement; Reproducibility of Results; Sensitivity and Specificity; Specimen Handling; Transducers;

fLanguage

English

Publisher

ieee

Conference_Titel

Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE

Conference_Location

Lyon

ISSN

1557-170X

Print_ISBN

978-1-4244-0787-3

Type

conf

DOI

10.1109/IEMBS.2007.4352952

Filename

4352952