Title :
An adaptive ISFET chemical imager chip
Author :
Georgiou, Pantelis ; Toumazou, Chris
Author_Institution :
Inst. of Biomed. Eng., Imperial Coll. London, London
Abstract :
A CMOS based ion sensitive chemical imager chip is presented for real time spatio- temporal monitoring of chemical activity. Ion-sensitive field effect transistors (ISFETs) implemented on an unmodified process (AMS 0.35 um) are used as the chemical input to the analogue circuits. A 3 x 11 array has been designed and fabricated for monitoring applications such as cell metabolism and growth. Chemical sensor information is encoded using integrate and fire neurons with address event representation (AER) used to fan out the data. Global adaptive biasing of pixels is used to conserve power and allow automatic functionality in changing buffer concentrations.
Keywords :
CMOS image sensors; chemical sensors; field effect transistors; CMOS based ion sensitive chemical imager chip; adaptive ISFET chemical imager chip; address event representation; cell growth; cell metabolism; chemical activity; chemical sensor; global adaptive biasing; ion-sensitive field effect transistors; real time spatio-temporal monitoring; Biosensors; CMOS image sensors; Chemical and biological sensors; Chemical engineering; Chemical sensors; Circuits; Intelligent sensors; Monitoring; Sensor arrays; Threshold voltage;
Conference_Titel :
Circuits and Systems, 2008. ISCAS 2008. IEEE International Symposium on
Conference_Location :
Seattle, WA
Print_ISBN :
978-1-4244-1683-7
Electronic_ISBN :
978-1-4244-1684-4
DOI :
10.1109/ISCAS.2008.4541858
