An implantable optrode with Self-diagnostic function in 0.35µm CMOS for optical neural stimulation

Author

Hubin Zhao ; Sokolov, Danil ; Degenaar, Patrick

Author_Institution

Sch. of Electr. & Electron. Eng., Newcastle Univ., Newcastle upon Tyne, UK

fYear

2014

fDate

22-24 Oct. 2014

Firstpage

244

Lastpage

247

Abstract

One of the key challenges in the optogenetic field is to develop novel optical delivery devices that have the feasibility for implantable neural stimulation. In this paper, a CMOS-Gallium Nitride based optrode is proposed for neural stimulation with optogenetic methodology. The optrode base unit has been designed in a X-Fab 0.35um CMOS process and consists of control and sensing circuitry and six stimulation centres. Each centre has connection points for connecting three micro light emitting diodes (LEDs) to achieve local light delivery. In addition, we develop a self-diagnostic function to monitor working condition of LEDs in real time. This strategy highly improves the reliability and safety of the optrode for implantable applications.

Keywords

CMOS image sensors; biomedical equipment; fibre optic sensors; light emitting diodes; neurophysiology; patient diagnosis; patient monitoring; prosthetics; CMOS-gallium nitride-based optrode; LED; X-Fab CMOS process; implantable applications; implantable neural stimulation; implantable optrode; local light delivery; microlight emitting diodes; optical delivery devices; optical neural stimulation; optogenetic field; optogenetic methodology; self-diagnostic function; size 0.35 mum; CMOS integrated circuits; Laser beam cutting; Light emitting diodes; Prosthetics; Retina; Silicon; Transistors;

fLanguage

English

Publisher

ieee

Conference_Titel

Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE

Conference_Location

Lausanne

Type

conf

DOI

10.1109/BioCAS.2014.6981708

Filename

6981708