Title :
An implantable image sensor with self-reset function for brain imaging
Author :
Sasagawa, Kiyotaka ; Yamaguchi, Toru ; Haruta, Makito ; Sunaga, Yoshinori ; Takehara, Hironari ; Noda, Toshio ; Tokuda, Takashi ; Ohta, Jun
Author_Institution :
Grad. Sch. of Mater. Sci., Nara Inst. of Sci. & Technol., Ikoma, Japan
Abstract :
We designed and fabricated an implantable image sensor high peak signal-to-noise ratio (SNR). In bio-imaging, it is often necessary to observe small changes of fluorescence, absorption, scattering. The peak SNR of a image sensor is limited by the shot-noise, which is proportional to the square root of incident light intensity. In this study, we avoid pixel saturation by self-reset function integrated in a pixel and increase the peak SNR. The pixel size is 15μm × 15μm and the peak SNR is over 60 dB We also demonstrated blood flow imaging of a rat brain surface by using the sensor.
Keywords :
biomedical optical imaging; brain; fluorescence; haemodynamics; image sensors; prosthetics; SNR; bioimaging; blood flow imaging; brain imaging; fluorescence; implantable image sensor; incident light intensity; rat brain surface; self-reset function; signal-to-noise ratio; Blood; Brain; Image sensors; Lighting; PSNR;
Conference_Titel :
Biomedical Circuits and Systems Conference (BioCAS), 2014 IEEE
Conference_Location :
Lausanne
DOI :
10.1109/BioCAS.2014.6981710
